The Jeremy Kyle Show was axed by ITV following the death of a guest that took part.
Later filming the series, during which he took a lie detector 23, steve Dymond was found dead May.
ITV’s chief executive Carolyn McCall said that the decision was a consequence of the”gravity of current events”.
The channel had suspended filming.
On Tuesday, the prime minister’s spokesman called Mr Dymond’s departure”deeply about”.
The Jeremy Kyle Show, has been the very popular programme in ITV’s daytime program, with an average of one million viewers and a 22% audience share.
The episode Mr Dymond participate in was based on the subject of infidelity.
A part of the crowd who had been in the recording told BBC News that Mr Dymond”dropped into the floor” and was”sobbing” when he failed the lie detector test.
Lie detectors were a fixture to the programme, which often featured disputes between household members and spouses.
Critics said it place people on a public platform, with problems of addiction and mental health – bringing a degree of exposure to them they may not have expected.
Following the death of Mr Dymond, ITV took episodes off the air, including that the episode featuring Mr Dymond would never be screened.
Talking to BBC Radio 4’s World At One programme, former ITV chief executive Stuart Prebble said that the blackout is”a good choice”, but producers”do take seriously their duty of care”.
He said:”I think that they will have known that they were in very sensitive land. I would never have mimicked this programme when I’d had any involvement.
“The manufacturers of these programmes walk a very thin line and also they understand they do. If you are close to the border as I think this show did it maybe not surprising that some thing like this will happen.
“They [ITV] have done the ideal thing – a quick and efficient review, and also the faster these things are dealt with all the greater.”
A spokesman for broadcasting regulator Ofcom said:”While ITV has decided to cancel the programme, its investigation into what happened is continuing and we will examine the findings “
ITV’s statement in full:
“Given the gravity of recent events we’ve decided to end production of The Jeremy Kyle Show.
“The Jeremy Kyle Show has experienced a loyal audience and has been produced by a dedicated production team for 14 decades, but today is the ideal time for the show to end.
“Everyone at ITV’s thoughts and sympathies are with all the family and friends of Steve Dymond.
“The previously announced review of this episode of this show is under way and will last.
“ITV will continue to work together with Jeremy Kyle on different projects.”